MATCHSTAT

Buffalo Bills vs New Orleans Saints: Prediction, Head-to-Head, Odds & Stats (Sun, 28 Sep '25)

Wojtek Kolan

Wojtek Kolan

Published on 28 Sep, 05:00 PM UTC

Next Match 28/09/25 at 05:00 PM

Buffalo Bills vs New Orleans Saints
📍 Highmark Stadium, USA.

Scheduled H2H Match For Buffalo Bills Vs New Orleans Saints

NFL

Sun, 28 Sep 2025 at 05:00 PM UTC

Buffalo Bills
Buffalo Bills

USA USA

Recent Form

W
W
W
W
L
New Orleans Saints
New Orleans Saints

USA USA

Recent Form

L
L
L
L
D

1

Win

Played

3
0 Draws

2

Win

2
Position
28
Sean McDermott
Manager
Kellen Moore

Game Schedule - Time Of Fixture

Buffalo Bills will square off vs New Orleans Saints in NFL on Sun, 28 Sep 2025 at 05:00 PM UTC. Let’s investigate historical performances, recent stats and head-2-head information to find out the most accurate picks and best bets.

Buffalo Bills vs New Orleans Saints H2H Game Summary

Analyzing the most recent 3 head-2-head fixtures for these teams, Buffalo Bills have got the victory 1 times and New Orleans Saints have got the victory on 2 occasion. In the most recent game between them, Buffalo Bills won 6-31.


Head-to-HeadMatch Wins
Buffalo Bills1
New Orleans Saints2

Matchstat.com Buffalo Bills vs New Orleans Saints Prediction For This Upcoming H2H Match

Buffalo Bills vs New Orleans Saints Premium Model Predictions With Edge

NFL.
Saints vs. B…
.28 Sept 25 at 05:00 PM
Under 46.5
Probability:
53.45%
Edge:
1.05%
Odds:
-110
NFL.
Saints vs. B…
.28 Sept 25 at 05:00 PM
Saints win
Probability:
16%
Edge:
-1%
Odds:
+490

This data is only Bookie Predictions.

Unlock all our Expert winning predictions by becoming a member.

GET AMERICAN FOOTBALL PRO
NFL.
Saints vs. B…
.28 Sept 25 at 05:00 PM
Saints +13.5
Probability:
Edge:
3.25%
Odds:
View All NFL Predictions With Edge picks

Buffalo Bills vs New Orleans Saints Past H2H Matches

9464
NFL
01:20 AM
26/11/21
4425
New Orleans Saints
6
4414
Buffalo Bills
31
06:00 PM
12/11/17
4414
Buffalo Bills
10
4425
New Orleans Saints
47
06:00 PM
09/09/01
4414
Buffalo Bills
6
4425
New Orleans Saints
24

Team Streaks

4414
Wins
4
4425
Losses
4
4425
No wins
10

Buffalo Bills Recent Matches

9464
NFL (24 Matches)
12:15 AM
19/09/25
4414
Buffalo Bills
31
4287
Miami Dolphins
21
W
05:00 PM
14/09/25
4427
New York Jets
10
4414
Buffalo Bills
30
W
12:20 AM
08/09/25
4414
Buffalo Bills
41
4413
Baltimore Ravens
40
W
11:30 PM
26/01/25
4422
Kansas City Chiefs
32
4414
Buffalo Bills
29
L
11:30 PM
19/01/25
4414
Buffalo Bills
27
4413
Baltimore Ravens
25
W
06:00 PM
12/01/25
4414
Buffalo Bills
31
4418
Denver Broncos
7
W
06:00 PM
05/01/25
4424
New England Patriots
23
4414
Buffalo Bills
16
L
06:00 PM
29/12/24
4414
Buffalo Bills
40
4427
New York Jets
14
W
09:25 PM
22/12/24
4414
Buffalo Bills
24
4424
New England Patriots
21
W
09:25 PM
15/12/24
4419
Detroit Lions
42
4414
Buffalo Bills
48
W
09:25 PM
08/12/24
4387
Los Angeles Rams
44
4414
Buffalo Bills
42
L
01:20 AM
02/12/24
4414
Buffalo Bills
35
4389
San Francisco 49ers
10
W
09:25 PM
17/11/24
4414
Buffalo Bills
30
4422
Kansas City Chiefs
21
W
06:00 PM
10/11/24
4421
Indianapolis Colts
20
4414
Buffalo Bills
30
W
06:00 PM
03/11/24
4414
Buffalo Bills
30
4287
Miami Dolphins
27
W
08:05 PM
27/10/24
4430
Seattle Seahawks
10
4414
Buffalo Bills
31
W
05:00 PM
20/10/24
4414
Buffalo Bills
34
4431
Tennessee Titans
10
W
12:15 AM
15/10/24
4427
New York Jets
20
4414
Buffalo Bills
23
W
05:00 PM
06/10/24
4324
Houston Texans
23
4414
Buffalo Bills
20
L
12:20 AM
30/09/24
4413
Baltimore Ravens
35
4414
Buffalo Bills
10
L
11:30 PM
23/09/24
4414
Buffalo Bills
47
4386
Jacksonville Jaguars
10
W
12:15 AM
13/09/24
4287
Miami Dolphins
10
4414
Buffalo Bills
31
W
05:00 PM
08/09/24
4414
Buffalo Bills
34
4412
Arizona Cardinals
28
W
11:30 PM
21/01/24
4414
Buffalo Bills
24
4422
Kansas City Chiefs
27
L
9465
NFL Preseason (6 Matches)
11:30 PM
23/08/25
4388
Tampa Bay Buccaneers
19
4414
Buffalo Bills
23
W
12:00 AM
18/08/25
4391
Chicago Bears
38
4414
Buffalo Bills
0
L
05:00 PM
09/08/25
4414
Buffalo Bills
25
4426
New York Giants
34
L
05:00 PM
24/08/24
4414
Buffalo Bills
26
4415
Carolina Panthers
31
L
11:00 PM
17/08/24
4345
Pittsburgh Steelers
3
4414
Buffalo Bills
9
W
05:00 PM
10/08/24
4414
Buffalo Bills
6
4391
Chicago Bears
33
L

New Orleans Saints Recent Matches

9464
NFL (24 Matches)
08:05 PM
21/09/25
4430
Seattle Seahawks
44
4425
New Orleans Saints
13
L
05:00 PM
14/09/25
4425
New Orleans Saints
21
4389
San Francisco 49ers
26
L
05:00 PM
07/09/25
4425
New Orleans Saints
13
4412
Arizona Cardinals
20
L
06:00 PM
05/01/25
4388
Tampa Bay Buccaneers
27
4425
New Orleans Saints
19
L
06:00 PM
29/12/24
4425
New Orleans Saints
10
4390
Las Vegas Raiders
25
L
01:15 AM
24/12/24
4420
Green Bay Packers
34
4425
New Orleans Saints
0
L
06:00 PM
15/12/24
4425
New Orleans Saints
19
4432
Washington Commanders
20
L
06:00 PM
08/12/24
4426
New York Giants
11
4425
New Orleans Saints
14
W
09:05 PM
01/12/24
4425
New Orleans Saints
14
4387
Los Angeles Rams
21
L
06:00 PM
17/11/24
4425
New Orleans Saints
35
4417
Cleveland Browns
14
W
06:00 PM
10/11/24
4425
New Orleans Saints
20
4393
Atlanta Falcons
17
W
06:00 PM
03/11/24
4415
Carolina Panthers
23
4425
New Orleans Saints
22
L
08:05 PM
27/10/24
4429
Los Angeles Chargers
26
4425
New Orleans Saints
8
L
12:15 AM
18/10/24
4425
New Orleans Saints
10
4418
Denver Broncos
33
L
05:00 PM
13/10/24
4425
New Orleans Saints
27
4388
Tampa Bay Buccaneers
51
L
12:15 AM
08/10/24
4422
Kansas City Chiefs
26
4425
New Orleans Saints
13
L
05:00 PM
29/09/24
4393
Atlanta Falcons
26
4425
New Orleans Saints
24
L
05:00 PM
22/09/24
4425
New Orleans Saints
12
4428
Philadelphia Eagles
15
L
05:00 PM
15/09/24
4392
Dallas Cowboys
19
4425
New Orleans Saints
44
W
05:00 PM
08/09/24
4425
New Orleans Saints
47
4415
Carolina Panthers
10
W
06:00 PM
07/01/24
4425
New Orleans Saints
48
4393
Atlanta Falcons
17
W
06:00 PM
31/12/23
4388
Tampa Bay Buccaneers
13
4425
New Orleans Saints
23
W
01:15 AM
22/12/23
4387
Los Angeles Rams
30
4425
New Orleans Saints
22
L
06:00 PM
17/12/23
4425
New Orleans Saints
24
4426
New York Giants
6
W
9465
NFL Preseason (6 Matches)
05:00 PM
23/08/25
4425
New Orleans Saints
19
4418
Denver Broncos
28
L
05:00 PM
17/08/25
4425
New Orleans Saints
17
4386
Jacksonville Jaguars
17
D
08:05 PM
10/08/25
4429
Los Angeles Chargers
27
4425
New Orleans Saints
13
L
06:00 PM
25/08/24
4425
New Orleans Saints
27
4431
Tennessee Titans
30
L
12:00 AM
19/08/24
4389
San Francisco 49ers
16
4425
New Orleans Saints
10
L
12:00 AM
11/08/24
4412
Arizona Cardinals
14
4425
New Orleans Saints
16
W

Buffalo Bills Next Fixtures

9464
NFL
05:00 PM
28/09/25
4414
Buffalo Bills
4425
New Orleans Saints
Prediction
12:20 AM
06/10/25
4414
Buffalo Bills
4424
New England Patriots
Prediction
11:15 PM
13/10/25
4393
Atlanta Falcons
4414
Buffalo Bills
Prediction
05:00 PM
26/10/25
4415
Carolina Panthers
4414
Buffalo Bills
Prediction
09:25 PM
02/11/25
4414
Buffalo Bills
4422
Kansas City Chiefs
Prediction
06:00 PM
09/11/25
4287
Miami Dolphins
4414
Buffalo Bills
Prediction
06:00 PM
16/11/25
4414
Buffalo Bills
4388
Tampa Bay Buccaneers
Prediction
01:15 AM
21/11/25
4324
Houston Texans
4414
Buffalo Bills
Prediction
09:25 PM
30/11/25
4345
Pittsburgh Steelers
4414
Buffalo Bills
Prediction
09:25 PM
07/12/25
4414
Buffalo Bills
4416
Cincinnati Bengals
Prediction
06:00 PM
14/12/25
4424
New England Patriots
4414
Buffalo Bills
Prediction
06:00 PM
21/12/25
4417
Cleveland Browns
4414
Buffalo Bills
Prediction
09:25 PM
28/12/25
4414
Buffalo Bills
4428
Philadelphia Eagles
Prediction
06:00 PM
04/01/26
4414
Buffalo Bills
4427
New York Jets
Prediction

New Orleans Saints Next Fixtures

9464
NFL
05:00 PM
28/09/25
4414
Buffalo Bills
4425
New Orleans Saints
Prediction
05:00 PM
05/10/25
4425
New Orleans Saints
4426
New York Giants
Prediction
08:25 PM
12/10/25
4425
New Orleans Saints
4424
New England Patriots
Prediction
05:00 PM
19/10/25
4391
Chicago Bears
4425
New Orleans Saints
Prediction
08:05 PM
26/10/25
4425
New Orleans Saints
4388
Tampa Bay Buccaneers
Prediction
09:05 PM
02/11/25
4387
Los Angeles Rams
4425
New Orleans Saints
Prediction
06:00 PM
09/11/25
4415
Carolina Panthers
4425
New Orleans Saints
Prediction
09:25 PM
23/11/25
4425
New Orleans Saints
4393
Atlanta Falcons
Prediction
06:00 PM
30/11/25
4287
Miami Dolphins
4425
New Orleans Saints
Prediction
06:00 PM
07/12/25
4388
Tampa Bay Buccaneers
4425
New Orleans Saints
Prediction
09:25 PM
14/12/25
4425
New Orleans Saints
4415
Carolina Panthers
Prediction
06:00 PM
21/12/25
4425
New Orleans Saints
4427
New York Jets
Prediction
06:00 PM
28/12/25
4431
Tennessee Titans
4425
New Orleans Saints
Prediction
06:00 PM
04/01/26
4393
Atlanta Falcons
4425
New Orleans Saints
Prediction

Buffalo Bills Last Match Played stats

Buffalo Bills vs Miami Dolphins

Final Score :31 - 21

(H)Offense (A)
4Touchdowns3
1/2Field goals0/0
360Total yards276
0Turnovers1
3/4Red zone efficiency3/3
31:47Time of Possession28:13
23First downs19
0First downs by penalty3
6/11 (54%)Third down efficiency10/15 (66%)
2Punts4
47.5Average yards per punt50
6.3Average yards per play4.7
(H)Passing (A)
12First downs by passing11
203Net yards passing146
213Gross yards passing146
3Passing touchdowns2
0Interceptions thrown1
6.8Average passing yards per attempt4.3
6Red zone passing attempts5
(H)Rushing (A)
27Rushing attempts25
157Rushing yards130
5.8Average rushing yards per attempt5.2
8First downs by rushing8
2Red zone rushing attempts5
(H)Other (A)
3Penalties6
35Yards penalized57
2Fumbles1
0Fumbles lost0

New Orleans Saints Last Match Played stats

Seattle Seahawks vs New Orleans Saints

Final Score :44 - 13

(H)Offense (A)
5Touchdowns1
3/3Field goals2/3
320Total yards284
1Turnovers1
4/5Red zone efficiency1/3
27:44Time of Possession32:16
22First downs21
5First downs by penalty4
3/9 (33%)Third down efficiency5/15 (33%)
2Punts6
46Average yards per punt40.5
5.9Average yards per play4.1
(H)Passing (A)
11First downs by passing12
233Net yards passing205
233Gross yards passing218
2Passing touchdowns1
0Interceptions thrown1
11.1Average passing yards per attempt4.8
6Red zone passing attempts4
(H)Rushing (A)
33Rushing attempts27
87Rushing yards79
2.6Average rushing yards per attempt2.9
7First downs by rushing4
3Red zone rushing attempts1
(H)Other (A)
8Penalties11
70Yards penalized77
1Fumbles0
1Fumbles lost0

NFL 25/26 Standings

POSTEAMMPWLPTS
1Philadelphia EaglesPhiladelphia Eagles3301
2San Francisco 49ersSan Francisco 49ers3301
3Los Angeles ChargersLos Angeles Chargers3301
4Buffalo BillsBuffalo Bills3301
5Indianapolis ColtsIndianapolis Colts3301
6Tampa Bay BuccaneersTampa Bay Buccaneers3301
7Green Bay PackersGreen Bay Packers3210.667
8Minnesota VikingsMinnesota Vikings3210.667
9Cincinnati BengalsCincinnati Bengals3210.667
10Seattle SeahawksSeattle Seahawks3210.667
11Washington CommandersWashington Commanders3210.667
12Pittsburgh SteelersPittsburgh Steelers3210.667
13Jacksonville JaguarsJacksonville Jaguars3210.667
14Arizona CardinalsArizona Cardinals3210.667
15Los Angeles RamsLos Angeles Rams3210.667
16Baltimore RavensBaltimore Ravens2110.5
17Detroit LionsDetroit Lions2110.5
18Cleveland BrownsCleveland Browns3120.333
19Atlanta FalconsAtlanta Falcons3120.333
20Chicago BearsChicago Bears3120.333
21Carolina PanthersCarolina Panthers3120.333
22Las Vegas RaidersLas Vegas Raiders3120.333
23Dallas CowboysDallas Cowboys3120.333
24Denver BroncosDenver Broncos3120.333
25Kansas City ChiefsKansas City Chiefs3120.333
26New England PatriotsNew England Patriots3120.333
27New York JetsNew York Jets3030
28Miami DolphinsMiami Dolphins3030
29New York GiantsNew York Giants3030
30Tennessee TitansTennessee Titans3030
31New Orleans SaintsNew Orleans Saints3030
32Houston TexansHouston Texans3030