Lazio vs Roma: Prediction, Head-to-Head, Odds & Stats (Sun, 21 Sep '25)

The forthcoming Serie A fixture is set to occur at the Stadio Olimpico in Italy on Sunday, 21st September 2025, local time. The game will feature a clash between Lazio and Roma, two teams with a storied rivalry. When evaluating the head-to-head matchups over their last three encounters, Roma holds the advantage with two victories, while Lazio is yet to secure a win. Only one match ended in a draw, which was the most recent meeting between them on Sunday, 13th April 2025.

Both teams are entering this match following similar setbacks. Lazio suffered a narrow 0-1 defeat against Sassuolo, showcasing their vulnerabilities that could be exploited. Similarly, Roma also faced a 0-1 loss at the hands of Torino, reflecting a shared recent struggle in form. Despite their recent performance slips, their standings in the domestic league present a different narrative. Lazio finds themselves positioned 12th, whereas Roma, with a comparatively stronger standing, resides in the 6th spot in the league.

Accurate predictions necessitate a detailed analysis of current form and streaks. Considering these statistics, Roma appears to be in a more advantageous position given their higher league standing and better head-to-head record. This suggests that Roma may likely emerge victorious in the upcoming contest, leveraging their historical performance against Lazio.